![]() All clinical data were obtained from medical records. The inclusion criteria for the study were as follows : 1) the subjects had been taking a stable dose of antihypertensive medication for at least 3 months, 2) radial tonometry data including radial argumentation index (rAI) and central blood pressure were available. The main results have been published previously. The chart review was performed until May 2013, and the event information was collected from each institution. From January 2007 to March 2011, the central blood pressure data were recorded from 4310 subjects enrolled throughout Japan. The study was approved by each participating institutional ethical board and was officially registered (UMIN000002966). Hypertension was defined as office blood pressure of >140/90 mmHg. As detailed previously, the ABC-J II study is an observational prospective study designed to evaluate the predictive value of central blood pressure on cardiovascular outcomes in hypertensive Japanese patients. The ABC-J II study is an expanded version of the original ABC-J study. To examine this possibility, a sub-analysis of the Antihypertensives and Blood Pressure of Central Artery in Japan (ABC-J) II study was performed. Because the reflection wave reaches the abdominal aorta sooner than the ascending aorta, it is conceivable that the impact of cPP is greater for cardiovascular (cardiac and brain) events than for renal events. Furthermore, the arterial stiffness gradient and pulse amplification are inverted during the progression of chronic kidney disease (CKD). The coronary and cerebral arteries originate from the thoracic aorta, while the renal arteries derive from the abdominal aorta. However, findings from the Framingham Heart Study suggested that central blood pressure was not predictive of cardiovascular disease events. examined the relationship of central blood pressure to incident cardiovascular events and concluded that cPP is more strongly related to cardiovascular events than brachial pressure. They reported that despite similar brachial blood pressure between treatments, there were substantial reductions of central pressure in the amlodipine-based group and that central pulse pressure (cPP) was associated with composite outcome of cardiovascular events. atenolol-based) regimens on central pressure. examined the impact of two different blood pressure-lowering (amlodipine-based vs. ![]() Just to the right or left of the windpipe.Central systolic blood pressure (SBP) is a direct pressure load on the heart and a stronger predictor of cardiovascular events than brachial systolic blood pressure. ![]() Use your index and middle fingers to find theĬarotid pulse The carotid pulse is found at the top of the neck Your thumb, which has a pulse of its own.īrachial pulse The brachial pulse is found on the inside of the Use your index and middle fingers to find it and not Radial pulse The radial pulse is found on the inside of the wristīelow the thumb. Retrieved from īyline: DR MIRIAM STOPPARD Helping to keep you fit and healthy
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